My sister usually takes all of her photos on her phone at the lowest setting possible so her selfies turn out teeny-tiny like that. I have some actions that I use in PS to resize them, and I have printed a few photos to hang in my house. They're at 4x6, and I haven't noticed anything 'wrong' with them. A few are grainy-looking but they looked that way in PS when I was playing with them.
I think you should be fine if you can finesse them a little in your program and don't make them much larger than 4x6.
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