My son had the exact same reaction to antibiotics when he was a year old. Its a reaction to the antibiots, but don't confuse that with ALLERGY. What my Connor had (and what your Callum probably has) is a harmless reaction to the antiobiotics. He'll probably grow out of it before he turns 2 (Connor did). It never bothered Connor. He was happy as a clam like nothing was going on.
BUT... its worth a call to the doc. You can never be too careful.
eta: I should add that Connor also had it EVERYWHERE. Palms of hand and feet, eyelids, groin, etc.
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