HELP - PSE won't work!

[scrappychic]

I'm using PSE 5 on Vista, I just started getting this runtime error. It won't let me open anything, save, even change fonts (the menu won't drop down). When I try to open something it give me a "can't perform operation" error and when I save it doesn't even give an error, it just won't do it.

Then when I shut it down, that's when I get the runtime error. I'm uninstalling it right now and will re-install after. You think that will help? I tried the repair way without unistalling but I kept getting the same errors, so I thought it would be best to do everything over.