When I was growing up, we had two male dogs. They were really sweet and friendly. Now that I'm an adult, I chose to get dogs, and we ended up with two females. There is NO difference at all, they're just as sweet and friendly as the boys. None of our dogs ever humped anyone's leg. LOL but they all have jumping-on-people issues (problem related to the breeds they are all not a behavioral issue)
One thing to think about, supposedly dogs tend to get more attached to people of the opposite sex- so if you were to get a boy, he'd be more attached to you than hubby