Sara,
I had six transfusions following my second birth. It was not scary. They'll give him Tylenol and benedryl before he gets the blood. Then it's just like an IV but it's blood. Feels no different.
Normally one unit takes three hours to get. Five of mine were done emergently so they took about three minutes each, hand pumped in. But my last one was a three hour one.
I'd be happy to talk to him about it if it will help ease his worries.
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