I have a 27" and I love it. I am 100% happy with my decision to get it, but I readily agree that the 21.5" would probably suit most people. When Kristin was deciding about which one to get, I did a couple screen shots to show how things look on a 27". In the first pic, the kit preview is at 12x12"... so a fullsize layout without needing to zoom in. In the second pic, you will see that I have the internet open plus I have enough room to have a fullsize document open next to it... and some extra room. I can have 2 fullsize internet screens side by side as well. I love my machine, but if something horrible happened to it and I had to buy a new one, I'd be tempted by the savings on getting the 21.5". Don't know if that helps your decision.