One of my kids had a year of recurrent ear infections. I learned that if the pain isn't gone by 3 days, the antibiotic probably isn't working and you should call the doctor. If it appears to go away but comes back as soon as the course of meds is over, then like everyone else said it wasn't fully gone. My other DS, who isn't prone to ear infections at all, got his first at age 3. It was a doozy--an antibiotic resistant double ear infection that persisted through 3 courses of antibiotics until they finally gave him an antibiotic shot that was much stronger.
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